Baldness Gene And Baldness Genetics

Baldness gene and baldness genetics

        Almost one third of all women have or will have a form of genetic alopecia (baldness), meaning baldness gene and baldness genetics. The cause of not growing new hair in women is not well understood but is associated with a genetic predisposition, with the aging (as related to menopause, fluctuations in hormone levels) and levels of endocrine hormones (particularly androgens - male hormones).

        The changes in the androgen hormone (male hormone) can affect hair production. For example, by hormonal changes due to menopause, many women find that their hair is thinner on the head while the hair on the face is thicker. Genetic aspect can also be a factor. Women whose family members are older, female, who were faced with the thinning of hair, are more likely to be subject to genetic alopecia. Women suffering from genetic alopecia do not lose hair as men do. Usually, the frontal hair line remains, but hair loss can be observed as a general thinning of hair on top and front of the head. Thinning hair usually begins in the crown and progresses.

        The family of male hormones known as androgens was established as a cause of genetic alopecia in men and women. Women have these "male hormones", but in smaller quantities. When the amount is increasing due to menopause, aging or other factors could lead to so-called genetic hair loss. Besides the fact that androgen levels increase, women are more sensitive to male hormones, even if they are in normal amounts. In people with a genetic predisposition for hair loss, a group of hormones called androgens (testosterone, androstestosterone, dihydrotestosterone - DHT) affect the natural process. These hormones are produced naturally in large quantities by the male body, so they are called "male hormones".

        When testosterone comes into contact with existing enzymes in the hair cell, is transformed into a stronger androgen called DHT, which then combines with hair follicle receptors. "Over time, the excess of DHT in hair follicles causes hair reduction, which in turn affects the rest period and the hair growth period" said Dr. Michael Reed, MD, Ph.D. associate dermatologist at NYU Medical Center clinic, and specialist in hair loss in women.

        If a person have the baldness gene and baldness genetics, baldness is permanent, but doctors prescribes anti-androgen medicines. For women, 2% Minoxidil formula (administered solution on the scalp) is a good option.

Baldness gene

       A gene whose absence causes partial or total hair loss was identified by the Japanese researchers, the discovery opening the way for new treatments against baldness. Japanese researchers have described how they managed to obtain genetically modified mice, without having a gene in their genetic structure. That gene is the Sox21 gene. "The mice began to change their fur exactly in the 11th day of life, starting from the head and progressing to the tail.

        When they reached the age of 20-25 days, these mice had no a wire of hair on the body, not even whiskers. The new hair began to grow after several days, but it fell after a new cycle, "explained the Japanese researchers. This cyclical baldness continued for over two years, and researchers noticed that the older genetically modified mice had sebaceous glands around the hair roots and their skin became thicker during the period when losing the fur.